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How to Avoid Gelation of Hyaluronic Acid?

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What is the "Mantou Effect" of Hyaluronic Acid?

The "mantou effect" refers to the abnormal swelling, excessive puffiness, or even deformation that occurs after hyaluronic acid (HA) injections. It gives the face a bloated appearance, similar to a "steamed bun" (mantou), with unnatural and stiff lines that lose their natural beauty. Hyaluronic acid injections are a popular aesthetic treatment to fill facial hollows, improve contours, and enhance skin elasticity and radiance. However, some individuals experience this undesired outcome after the procedure.
 
One possible cause of the "mantou effect" is the use of crosslinking agents in the hyaluronic acid formulation. Crosslinking agents are added to make the hyaluronic acid gel more stable and longer-lasting. However, depending on the type or concentration of the crosslinking agent used, the HA can become too thick or retain excess water, leading to unnatural swelling or "lumps" under the skin.

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How Do Crosslinking Agents Contribute to the "Mantou Effect"?

 
1. Increased Viscosity and Hardness

Crosslinking agents cause hyaluronic acid molecules to form a stable, mesh-like structure, which increases the viscosity and hardness of the product. High-viscosity hyaluronic acid does not spread or flow easily after injection, especially in superficial layers of the skin. This can result in localized accumulation, causing unnatural puffiness or lump formation, contributing to the "mantou effect."

 

2. Enhanced Water Absorption Leading to Swelling

Crosslinked hyaluronic acid has a strong water-absorbing capacity. After being injected into the skin, it draws in surrounding moisture and swells. If the degree of crosslinking is too high, the water absorption is significantly increased, leading to excessive swelling in the injected area. This can make facial contours appear stiff and unnatural.

 

3.Uneven Distribution and Difficulty in Metabolism

Crosslinking agents increase the stability of hyaluronic acid molecules, making it less likely to distribute evenly within the skin and harder to metabolize. When hyaluronic acid remains in the same area for a prolonged period, especially in superficial layers of the skin, it may cause localized swelling, which is one of the common causes of the "mantou effect."

How to Avoid the "Mantou Effect" with Hyaluronic Acid Injections

  • Choose an Experienced Doctor
    An experienced doctor can accurately assess your facial condition, choose the right type of hyaluronic acid, and determine the correct injection dosage. Their expertise ensures precise injection techniques, reducing the risk of complications like the "mantou effect."
  • Opt for Small Amounts Over Multiple Sessions
    Avoid injecting too much hyaluronic acid at once. Instead, opt for smaller doses over several sessions. This allows the doctor to assess the results gradually and make adjustments as needed, ensuring more natural outcomes.
  • Choose the Right Type of Hyaluronic Acid
    Different areas of the face require different types of hyaluronic acid. An experienced physician will select the most suitable product for your specific needs, ensuring better integration and minimizing the risk of uneven distribution or swelling.
  • Post-Treatment Care
    Follow the post-treatment care instructions provided by your doctor. Proper aftercare promotes even distribution and absorption of the hyaluronic acid, helping to prevent the occurrence of unnatural puffiness or lumps.

Can the "Mantou Effect" Be Improved?

If the "mantou effect" occurs after hyaluronic acid injection, it can be addressed with the help of a medical professional. Depending on the situation, the following measures may be taken:
  • Hyaluronic Acid Degradation
    If too much hyaluronic acid was injected, the doctor can use hyaluronidase (hyaluronic acid dissolving enzyme) to break down the excess filler, restoring the natural contours.
  • Massage
    In some cases, gentle massage may help to distribute the hyaluronic acid more evenly, aiding in the reduction of uneven bulging or swelling.
  • Other Supportive Treatments
    Depending on the severity, the doctor may recommend additional treatments like ultrasound lifting or radiofrequency therapy. These treatments can help tighten and firm the skin, improving overall appearance and reducing the effects of uneven filler distribution.

Choosing HYADERMIS and ANIMERS to Avoid "Mantou Effect"

The use of patented technologies such as BDDE and CHAP in products like HYADERMIS and ANIMERS helps to prevent the "mantou effect" caused by excessive bulging or uneven distribution of hyaluronic acid. These advanced technologies ensure that the hyaluronic acid fills and contours the skin naturally while minimizing the risk of accumulation or displacement.

Moreover, as time passes, these hyaluronic acid products gradually break down and are metabolized by the body, ensuring a safe and natural absorption process with no residuals left behind. This makes HYADERMIS and ANIMERS a reliable option for achieving long-lasting, natural results without causing the unwanted "mantou" effect.

 

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